{"meta":{},"result":{"jobOpening":{"jobOpeningShareUrl":"https:\/\/orumtherapeutics.bamboohr.com\/careers\/95","jobOpeningName":"Bioanalytical Scientist ","jobOpeningStatus":"Open","jobCategoryId":null,"departmentId":"18597","departmentLabel":"Chemistry","employmentStatusLabel":"Full Time KR","location":{"city":"Daejeon","state":"Korea","postalCode":"34050","addressCountry":"Korea (South)"},"atsLocation":{"country":null,"countryId":null,"state":null,"city":null},"description":"<p><span style=\"font-size: 14pt; font-weight: bold\">Bioanalytical Scientist<\/span><br><\/p>\n<p>Chemistry<\/p>\n<p><span>Start Date: 6\/15\/2026<\/span><\/p>\n<p><span>Location: Daejeon office, KR<\/span><span>\u202f (<\/span><span>Hybrid<\/span><span>: <\/span><span>Yes<\/span><span>)<\/span><\/p>\n<p><span>\u00a0<\/span><\/p>\n<p><span style=\"font-weight: bold\"><span>General Summary<\/span><\/span><span>\u00a0<\/span><\/p>\n<p>\uc624\ub984\ud14c\ub77c\ud4e8\ud2f1\uc740 Bioanalytical(BioA) \ubc0f PK\/PD \uae30\ub2a5\uc744 \ub9ac\ub529\ud560 \uc5ed\ub7c9 \uc788\ub294 Scientist\ub97c \ucc3e\uace0 \uc788\uc2b5\ub2c8\ub2e4.<br>\ubcf8 \ud3ec\uc9c0\uc158\uc740 \ud56d\uccb4\uc640 \uc18c\ubd84\uc790 \ubd84\uc11d\uc758 \uad50\ucc28 \uc601\uc5ed\uc5d0\uc11c, \ud2b9\ud788 ADC(Antibody-Drug Conjugate)\uc758 \ubcf5\uc7a1\ud55c \ud2b9\uc131\uc744 \uc815\ubc00\ud558\uac8c \ubd84\uc11d\ud558\uace0 \ud574\uc11d\ud558\ub294 \uc5ed\ud560\uc744 \uc218\ud589\ud569\ub2c8\ub2e4.<br>\ud574\ub2f9 \ud3ec\uc9c0\uc158\uc740 \ub0b4\ubd80 \ubd84\uc11d\ubc95 \uac1c\ubc1c\ubd80\ud130 \uae00\ub85c\ubc8c CRO \uad00\ub9ac\uae4c\uc9c0 bioanalytical \uc804\ubc18\uc744 \ucd1d\uad04\ud558\uba70, GLP\/GCP \ud658\uacbd\uc5d0\uc11c \uc2e0\ub8b0\ub3c4 \ub192\uc740 \ub370\uc774\ud130\ub97c \uc0dd\uc131\ud558\ub294 \ub370 \ud575\uc2ec\uc801\uc778 \uc5ed\ud560\uc744 \ud569\ub2c8\ub2e4. \ub610\ud55c \ub2e8\uc21c \ubd84\uc11d\uc744 \ub118\uc5b4, PK \ub370\uc774\ud130\ub97c \uae30\ubc18\uc73c\ub85c \uc778\uc0ac\uc774\ud2b8\ub97c \ub3c4\ucd9c\ud558\uace0 \ud6c4\ubcf4\ubb3c\uc9c8 \uc120\uc815 \ubc0f \uac1c\ubc1c \uc804\ub7b5\uc5d0 \uae30\uc5ec\ud558\ub294 \uc804\ub7b5\uc801 \ud30c\ud2b8\ub108\ub85c\uc11c \ud504\ub85c\uc81d\ud2b8 \ud300\uacfc \uae34\ubc00\ud788 \ud611\uc5c5\ud558\uac8c \ub429\ub2c8\ub2e4.<\/p>\n<p><br><\/p>\n<p><span style=\"font-size: 14pt; font-weight: bold\">\uc8fc\uc694\uc5c5\ubb34<\/span><\/p>\n<ul>\n<li>\uc57d\ubb3c \ucd5c\uc801\ud654\ubd80\ud130 IND \uc81c\ucd9c\uae4c\uc9c0 ADC \ub610\ub294 \ubc14\uc774\uc624\uc758\uc57d\ud488 \ud504\ub85c\uadf8\ub7a8\uc744 \uc704\ud55c bioanalytical PK\/PD \uc804\ub7b5 \uc218\ub9bd \ubc0f \uc218\ud589<\/li>\n<li>Total antibody \ubc0f conjugated &amp; free payload \ub4f1 \ub2e4\uc911 \ubd84\uc11d \ub300\uc0c1 \uae30\ubc18\uc758 bioanalytical \ubd84\uc11d \uc124\uacc4 \ubc0f \uc6b4\uc601<\/li>\n<li>In vitro \ubc0f in vivo ADME \uc5f0\uad6c(\ub300\uc0ac, \uc57d\ubb3c\uc0c1\ud638\uc791\uc6a9 \ub4f1) \uc218\ud589 \ub610\ub294 \uad00\ub9ac<\/li>\n<li>LC-MS\/MS \ubc0f Ligand-Binding Assay(LBA) \uae30\ubc18\uc758 \ubd84\uc11d \uc218\ud589 \ub610\ub294 \uad00\ub9ac<\/li>\n<li>\uc678\ubd80 CRO\uc640 \ud611\uc5c5\ud558\uc5ec method transfer, development, validation, trouble shooting \uc9c4\ud589 \ubc0f \uad00\ub9ac<\/li>\n<li>GLP\/GCP \uae30\uc900\uacfc FDA \uc9c0\uce68\uc5d0 \ub530\ub978 SOP, validation report, bioanalytical \uc5f0\uad6c \uacc4\ud68d \uac80\ud1a0 \ubc0f \uc2b9\uc778<\/li>\n<li>\ub2e4\ud559\uc81c\uac04 \ud504\ub85c\uc81d\ud2b8\uc758 Bioanalysis\/PK \ubd84\uc57c Subject Matter Expert(SME) \uc5ed\ud560 \uc218\ud589<\/li>\n<li>R&amp;D \ubc0f Clinical \ub4f1 \uc720\uad00 \ubd80\uc11c\uc640 \ud611\uc5c5\uc744 \ud1b5\ud574 \ud504\ub85c\uc81d\ud2b8 \ub9c8\uc77c\uc2a4\ud1a4 \ub2ec\uc131 \uc9c0\uc6d0<\/li>\n<li>IND\/IB \ub4f1 \uaddc\uc81c \uc81c\ucd9c \ubb38\uc11c \uc791\uc131 \uc2dc BioA, PK \uc139\uc158 \ucc45\uc784 \uc9d1\ud544 \ubc0f GLP\/GCP\uc640 FDA\/EMA\uc758 bioanalytical \uc9c0\uce68 \uc644\uc804 \uc900\uc218 \ubcf4\uc7a5<\/li>\n<\/ul>\n<p><span style=\"font-size: 14pt; font-weight: bold\">\uc790\uaca9\uc0ac\ud56d<\/span><\/p>\n<ul>\n<li>Analytical Chemistry \ub610\ub294 \uad00\ub828 \ubd84\uc57c \ubc15\uc0ac \uc774\uc0c1 \ud559\uc704 \ubc0f \ud559\uc704 \ucde8\ub4dd \ud6c4 5\ub144 \uc774\uc0c1\uc758 \uad00\ub828 \uacbd\ub825<\/li>\n<li>LC-MS\/MS \ubc0f LBA \ub4f1\uc758 \ubd84\uc11d\ubc95 \ud65c\uc6a9\uc744 \ud65c\uc6a9\ud55c ADC \uc57d\ubb3c\uc758 PK \ubc0f \uc0dd\uccb4 \ub0b4 \ubd84\ud3ec (biodistribution) \uc5f0\uad6c \uacbd\ud5d8<\/li>\n<li>Total antibody, Free\/Conjugated payload \ubc0f \ud56d-\uc57d\ubb3c \ud56d\uccb4 (ADA) \ubd84\uc11d\uc744 \ud3ec\ud568\ud55c ADC \ubaa8\ub2ec\ub9ac\ud2f0\uc6a9 \ubc14\uc774\uc624 \ubd84\uc11d\ubc95 \uac1c\ubc1c, \uac80\uc99d \ubc0f \uc2e4\ud589<\/li>\n<li>\ucd08\uae30 \ud0c0\ub2f9\uc131 \uac80\ud1a0\ubd80\ud130 \ud6c4\ubcf4\ubb3c\uc9c8 \uc120\uc815(Candidate nomination) \ub2e8\uacc4\uc758 \uc2a4\ud06c\ub9ac\ub2dd \uc804\ub7b5\uc744 \ud3ec\ud568, ADME \uc6d0\uce59 \ubc0f \uc2e0\uc57d \uac1c\ubc1c \uc6cc\ud06c\ud50c\ub85c\uc6b0\uc5d0 \ub300\ud55c \uc2ec\ub3c4 \uc788\ub294 \uc774\ud574<\/li>\n<li>PK \ub370\uc774\ud130\uc758 \ube44\uad6c\ud68d \ubd84\uc11d(NCA) \uacbd\ud5d8<\/li>\n<li>GLP \ubc0f GCP \uaddc\uc815\uacfc \uc774\ub97c \ubc14\uc774\uc624 \ubd84\uc11d \ubc0f \uc784\uc0c1 \uc5f0\uad6c \ud658\uacbd\uc5d0 \uc801\uc6a9\ud558\ub294 \ubc29\ubc95\uc5d0 \ub300\ud55c \uc2e4\ubb34 \uc9c0\uc2dd \ubc0f \uc219\ub2ec<\/li>\n<li>\uc2e0\uc57d\uac1c\ubc1c \ud504\ub85c\uc138\uc2a4 \ubc0f \uc57d\ub3d9\ud559(PK)\uc5d0 \ub300\ud55c \uc774\ud574<\/li>\n<li>CRO \ub610\ub294 \uc678\ubd80 \ud30c\ud2b8\ub108\uc640\uc758 \ud611\uc5c5 \uacbd\ud5d8<\/li>\n<li>\ub370\uc774\ud130 \ud574\uc11d \ubc0f \ubb38\uc81c \ud574\uacb0 \ub2a5\ub825<\/li>\n<\/ul>\n<p><span style=\"font-size: 14pt; font-weight: bold\">\uc6b0\ub300\uc0ac\ud56d<\/span><\/p>\n<ul>\n<li>ADC \ub610\ub294 \ubcf5\uc7a1\ud55c biologics \ubd84\uc11d \uacbd\ud5d8 \ubcf4\uc720\uc790<\/li>\n<li>Bioanalytical assay \uac1c\ubc1c \ubc0f validation \uacbd\ud5d8<\/li>\n<li>ADME \uc5f0\uad6c \uacbd\ud5d8<\/li>\n<li>IND\/IB \ub4f1 \uaddc\uc81c \ubb38\uc11c \uc791\uc131 \uacbd\ud5d8<\/li>\n<li>PK\/PD \ubaa8\ub378\ub9c1 \ubc0f \uc2dc\ubbac\ub808\uc774\uc158, \uc9d1\ub2e8 \uc57d\ub3d9\ud559(PopPK) \ubd84\uc11d, \uba54\ud0c0 \ubd84\uc11d \uc2e4\ubb34 \uacbd\ud5d8<\/li>\n<li>\uae00\ub85c\ubc8c \ud658\uacbd\uc5d0\uc11c\uc758 \ud611\uc5c5 \ubc0f \ucee4\ubba4\ub2c8\ucf00\uc774\uc158 \uacbd\ud5d8<\/li>\n<li>\ube60\ub974\uac8c \ubcc0\ud654\ud558\ub294 \uc870\uc9c1\uc5d0\uc11c\uc758 \uc5c5\ubb34 \uc218\ud589 \uacbd\ud5d8<\/li>\n<li>\ub192\uc740 \ucc45\uc784\uac10\uacfc \uc8fc\ub3c4\uc131, \uc2e4\ud589\ub825<\/li>\n<li>\ub2e4\uc218\uc758 \ud504\ub85c\uc81d\ud2b8\ub97c \ud6a8\uacfc\uc801\uc73c\ub85c \uad00\ub9ac\ud560 \uc218 \uc788\ub294 \uc5ed\ub7c9<\/li>\n<\/ul>\n<p><br><\/p>\n<p>\uc774\ub825\uc11c\ub294 \ub2f9\uc0ac \uacf5\uc2dd \ucc44\uc6a9 \ud648\ud398\uc774\uc9c0(<a href=\"https:\/\/www.orumrx.com\/careers\" target=\"_blank\" rel=\"noopener noreferrer\">Careers | Apply Now \u2014 Orum Therapeutics<\/a>)\ub97c \ud1b5\ud55c \uc9c0\uc6d0\uc744 \uc6b0\uc120\uc2dc\ud569\ub2c8\ub2e4.<br>\uc9c0\uc6d0 \uc2dc *\uc601\ubb38 \uc774\ub825\uc11c(\ud544\uc218)\uc640 \uad6d\ubb38 \uc774\ub825\uc11c\ub97c<span>\u00a0<\/span>\ud558\ub098\uc758 PDF \ud30c\uc77c\ub85c \uc800\uc7a5\ud558\uc5ec \uc5c5\ub85c\ub4dc\ud574\uc8fc\uc2dc\uae30 \ubc14\ub78d\ub2c8\ub2e4.<br>\u203b \ud55c\uae00(HWP\/Word) \ud30c\uc77c\uc740 \uc624\ub958\uac00 \ubc1c\uc0dd\ud560 \uc218 \uc788\uc73c\ubbc0\ub85c \uc81c\ucd9c\uc744 \uc9c0\uc591\ud574\uc8fc\uc138\uc694.<br>\uc774\ub825\uc11c \ub0b4\uc5d0\ub294 \uc5f0\ubd09 \uc815\ubcf4\ub97c \uae30\uc7ac\ud558\uc9c0 \ub9d0\uace0, \uc9c0\uc6d0\uc11c \uc785\ub825\ub780\uc5d0\ub9cc \uc791\uc131\ud574\uc8fc\uc138\uc694.<span>\u00a0<\/span><\/p>\n<p><span><span style=\"color: rgb(29, 28, 29)\">\u203b \uc790\uaca9 \uc694\uac74 \ubc0f \uacbd\ub825\uc5d0 \ub530\ub77c \uc9c1\uae09\uacfc \ucc98\uc6b0\ub294 \ud611\uc758\ud558\uc5ec \ub0b4\ubd80 \uaddc\uc815\uc5d0 \ub530\ub77c \ucd5c\uc885 \uacb0\uc815\ub429\ub2c8\ub2e4. \ucc44\uc6a9 \ud615\ud0dc \ubc0f \uc218\uc2b5\uae30\uac04\uc740 \uad00\ub828 \ubc95\ub839\uacfc \ud68c\uc0ac \uc815\ucc45\uc5d0 \ub530\ub77c \uc801\uc6a9\ub418\uba70, \uc138\ubd80 \uc0ac\ud56d\uc740 \ucc44\uc6a9 \uacfc\uc815\uc5d0\uc11c \uc548\ub0b4\ub429\ub2c8\ub2e4.<\/span><\/span><\/p>\n<p><br><\/p>\n<p><br><\/p>\n<p>Orum Therapeutics is seeking a highly motivated and accomplished scientist to lead the Bioanalytical (BioA) and PK\/PD function. This role is designed for a technical expert who thrives at the intersection of large and small molecule analysis, specifically focused on the complex characterization of Antibody-Drug Conjugates (ADCs). As a key scientific lead, you will orchestrate the bioanalytical lifecycle \u2014 from internal method innovation to global CRO oversight \u2014 ensuring high-quality data generation in a GLP\/GCP environment. Beyond assay management, you will serve as a strategic partner in project teams, leveraging pharmacokinetic modeling to translate data into actionable insights that drive candidate selection and program progression.<br><\/p>\n<p><br><br><\/p>\n<p><span style=\"font-size: 14pt; font-weight: bold\">Principal Duties and Responsibilities<\/span><\/p>\n<ul>\n<li>Design and execute integrated Bioanalytical and PK\/PD strategies for ADC programs, utilizing the three-analyte quantification approach (Total Ab, Conjugated, and Free Payload) from lead optimization to IND filing.<\/li>\n<li>Oversee in vitro and in vivo ADME studies, including payload metabolism, drug-drug interactions (DDI), and transporter assays, to define the metabolic fate of the ADC and the released payload.<\/li>\n<li>Provide high-level technical oversight for hybrid bioanalytical workflows, specifically bridging LBA and LC-MS\/MS platforms to ensure robust quantification of complex modalities.<\/li>\n<li>Lead CRO selection and management, serving as the primary point of contact for method transfer, development, validation, and troubleshooting of proprietary assays under aggressive timelines.<\/li>\n<li>Review and approve SOPs, validation reports, and bioanalytical study plans in alignment with GLP\/GCP standards and current FDA guidance.<\/li>\n<li>Act as the BioA\/PK subject matter expert (SME) within multidisciplinary project teams, collaborating with Research &amp; Development and Clinical teams to drive program milestones.<\/li>\n<li>Drive continuous improvement by evaluating emerging technologies to enhance the throughput and quality of ADC characterization.<\/li>\n<li>Execute an integrated role that bridges high-level scientific leadership and direct lab-based contributions, ensuring seamless translation from internal innovation to external CRO execution.<\/li>\n<li>Serve as the lead author for BioA and PK sections of regulatory submissions (IND\/IB), ensuring full compliance with GLP\/GCP and current FDA\/EMA bioanalytical guidance.<\/li>\n<\/ul>\n<p><br><\/p>\n<p><span style=\"font-size: 14pt; font-weight: bold\">Skills, Abilities &amp; Competencies<\/span><\/p>\n<ul>\n<li>Extensive experience in pharmacokinetic (PK) and biodistribution studies of Antibody-Drug Conjugates (ADCs), including application of advanced bioanalytical methods such as LC-MS\/MS for small-molecule quantitation and MSD-based ligand-binding assays (LBAs).<\/li>\n<li>Proven track record in developing, validating, and implementing bioanalytical assays for ADC modalities, including total antibody, free and conjugated payload, and anti-drug antibodies (ADA) assays, in support of preclinical and clinical PK studies.<\/li>\n<li>In-depth understanding of ADME principles and drug discovery\/development workflows, including screening strategies from early feasibility through candidate nomination.<\/li>\n<li>Experience in non-compartmental analysis of PK data, with hands-on experience in PK\/PD modeling and simulation, population PK analysis, and meta-analysis is a plus.<\/li>\n<li>Working knowledge of GLP and GCP regulations and their application within bioanalytical and clinical study environments.<\/li>\n<li>Demonstrated ability to operate independently in fast-paced biotech settings while effectively collaborating within cross-functional, global teams.<\/li>\n<li>Excellent communication, organizational, and time-management skills, with the ability to manage multiple priorities and deliver high-quality results.<\/li>\n<li>Strong work ethic with a high degree of accountability, initiative, and ability to work with minimal supervision.<\/li>\n<\/ul>\n<p><br><\/p>\n<p><span style=\"font-size: 14pt; font-weight: bold\">Education<\/span><\/p>\n<p>Ph.D. or equivalent degree in Analytical Chemistry or a related field with a minimum of 5 years' experience. Level will be commensurate with experience and accomplishments.<\/p>\n<p><br><\/p>\n<p><span>Applications are<span style=\"font-size: 12pt\">\u00a0prioritized\u00a0<\/span>through our official careers website(<a href=\"https:\/\/www.orumrx.com\/careers\" target=\"_blank\" rel=\"noopener noreferrer\">Careers | Apply Now \u2014 Orum Therapeutics<\/a>).<br>Please combine your English (required) and Korean CV\u00a0 into a single PDF file before uploading.<br>\u203b Submissions in HWP\/Word format may cause file errors and are not recommended.<br>Please remove any salary information from your CV; such details should be entered only in the application form.<\/span><\/p>\n<p><span><span style=\"color: rgb(29, 28, 29)\">\u203b Career level, Employment type and any probationary period will be applied in accordance with applicable laws and company policy, with further details provided during the hiring process.<\/span><\/span><\/p>","compensation":null,"datePosted":"2026-04-28","minimumExperience":"Experienced","locationType":"0","seekPromoted":false},"formFields":{"firstName":{"isRequired":true,"value":"","label":"First Name"},"lastName":{"isRequired":true,"value":"","label":"Last Name"},"email":{"isRequired":true,"value":"","label":"Email"},"phone":{"isRequired":true,"value":"","label":"Phone"},"streetAddress":{"isRequired":true,"value":"","label":"Address"},"city":{"isRequired":true,"value":"","label":"City"},"state":{"isRequired":true,"value":"","label":"State","options":[]},"zip":{"isRequired":true,"value":"","label":"ZIP"},"countryId":{"isRequired":true,"value":"114","label":"Country","options":[{"id":"1","text":"United States"},{"id":"2","text":"Canada"},{"id":"3","text":"Australia"},{"id":"4","text":"Afghanistan"},{"id":"5","text":"Albania"},{"id":"6","text":"Algeria"},{"id":"7","text":"American 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